“Craig” (John Wayne) shows up in Sacramento, which is growing rapidly, after a disagreement on a riverboat, intending to establish his pharmacy. He’s not an unskilled practitioner, yet he struggles to locate suitable space. Fortunately, the woman responsible for soaking him earlier offers to lease him a storefront adjacent to her saloon. “Lacey” (Binnie Barnes) recognizes significant potential in this strong man, but…

A pharmacist named Tom Craig travels from Boston to Sacramento with aspirations of establishing his own pharmacy. During his journey, he finds himself at odds with Britt Dawson, a local tough who disapproves of Tom’s Eastern ways; however, Lacey Miller, Dawson's girlfriend, appreciates Tom’s demeanor, and together with a new acquaintance called Kegs McKeever, he begins to realize his ambitions, though Dawson and his …