The relentless pursuit of the Enforcers left Spider-Man with a precarious burden: shielding Norman Osborn from the wrath of the vengeful Vulture.

A laboratory mishap irrevocably alters Max Dillon, transforming him into the formidable supervillain Electro. He makes a singular demand of Dr. Martha Connors: she must find a cure for his condition, all while Spider-Man strives to halt his…

When Dr. Curt Connors’ experiment to regrow his lost arm takes a disastrous turn, transforming him into the monstrous Lizard, Peter, Martha, Eddie, and Gwen find themselves desperately seeking a cure.

At the behest of Kingpin, Hammerhead enlisted Montana for a perilous task: the acquisition of a sophisticated technological suit. The intended purpose was clear – to deploy the stolen technology as the Shocker, and in that guise, to inflict…

While Peter Parker and Harry Osborn pursue their aspirations to join the football team, Spider-Man confronts Flint Marko, recently empowered as the Sandman, who seeks to dismantle his existence.

While Otto maneuvers the Rhino into existence as a fresh diversion for Spider-Man, Peter heeds Aunt May’s counsel and extends an invitation to Mary Jane Watson for the high school prom.

Peter and Mary Jane were the talk of the Fall Formal. At the same time, the Green Goblin’s assault on Fisk Industries demanded Spider-Man's attention.

The Green Goblin’s grotesque fusion of Otto Octavius’s mechanical limbs with his own form birthed a new entity: Doctor Octopus. Now pursued relentlessly by Spider-Man, the newly formed villain must desperately seek a power source to sustain…

The crimson and blue figure of Spider-Man finds himself locked in conflict with the Green Goblin and Tombstone. Meanwhile, Colonel John Jameson struggles to guide a crippled spacecraft safely back to Earth.

Assuming the guise of Spider-Man, the Chameleon initiates a series of criminal acts, a threat only Spider-Man and the Black Cat can hope to overcome by working in concert.

Escaping confinement, the Sinister Six plotted their assault on Spider-Man, and for a time, their efforts seemed poised for triumph. Yet, Peter awoke afterward with a disconcerting blankness, the memory of the conflict vanished from his min…

Torn by the presence of the alien symbiote, Spider-Man’s past comes into sharp relief.

The creature known as Venom, a fusion of Eddie Brock and the alien symbiote, targets Spider-Man with cruel precision, striking at those closest to him.