Synopsis

The foundations of Derek and Addison’s relationship tremble when a former friend arrives at Seattle Grace, his presence threatening to disrupt the equilibrium of several staff members. Cristina and Burke’s connection is strained by the exposure of a long-held secret. Alex and Izzie grapple with their hidden feelings during the intensity of a Code Black crisis. Adding to the turmoil, an arrogant doctor deliberately provokes Derek at every turn. A patient's unusual affliction – experiencing consta