Synopsis

Cristina finds herself troubled by the newly imposed work restrictions for the year. Meanwhile, Izzie’s patient, Denny Duquette, desires two things with equal intensity: a heart transplant and Izzie herself. Addison finds Derek's trailer utterly distasteful, while Derek makes a visit to Meredith's mother. George attends to a young, transgender patient struggling with the frustrations of pre-pubescence. Elsewhere, patients exhibit peculiar behaviors, and the doctors’ relationships continue to unr