Andrea (played by Pierfrancesco Favino) and Sofia (Kasia Smutniak) form a couple that’s quite appealing, or at least they once did. After ten years of marriage, their relationship is struggling, and divorce seems like a possibility. However, due to an experiment conducted by Andrea, the pair unexpectedly swap places – inhabiting each other's bodies. Now, they are forced to experience life from the perspective of one another. He finds himself living as her, a television personality with aspirations for greater success, while she is now in his position as a neurosurgeon known for his brain research.

Source on TMDB