Cristiana Dell’Anna gives a powerful performance as the central figure, a nun committed to establishing orphanages in China for children suffering from illness and poverty. Her repeated requests to the Vatican for authorization—and financial support—have finally led to an invitation to Rome, only to be denied. Even then, she remains steadfast, and following a convincing meeting with Pope Leo XIII (Giancarlo Giannini), she secures permission to demonstrate her capabilities—though not in the location she desired, but rather New York. She is dispatched to the city's impoverished Five Points district, where an ordeal begins that challenges her resolve as the Archbishop’s (David Morse) primary concern appears to be placating the Mayor (John Lithgow), rather than supporting her goals for significant reform. It's notable that in a city built by immigrants, there was such division among the Italian, Jewish, and Irish communities, with little acceptance of one another. Cabrini comes to understand that neither her faith nor her position as a nun will be enough; she must enlist local street children and battle for every advancement. As this is based on historical events, we already know the eventual outcome, but producer Alejandro Monteverde has created a visually appealing depiction that still maintains suspense throughout her struggles. Her unwavering focus, stubbornness—balanced with considerable compassion and integrity—are effectively shown. The film boasts impressive visuals, and the story also highlights the limited opportunities available to women in what were considered progressive societies, both American and Italian, alongside an entrenched class structure that disregarded those living in less fortunate circumstances. It does feel somewhat lengthy; there are sections where the pacing falters and the narrative loses momentum, but overall it’s a moving account of a woman who was willing to make any sacrifice for those who were disadvantaged.

Source on TMDB